S U P R A C H E M
Think OUTSIDE The Bond
TM
SUPRAMOLECULAR ENGINEERING
Time To TRANSFORM CHEMISTRY in the Life Sciences
The net effect is to transform chemistry in how compounds are designed, how they are synthesized and how they function when deployed, adaptively. An example in the life sciences is molecular recognition of biomarkers, which are indicators of disease. Unlike any current therapeutic compound on the market today, SUPRACHEM adaptive compounds are designed to detect molecular biomarkers and respond to them by adjusting their chemical properties and biological activity. This results in marketable therapeutic products that are programmed to adjust to diverse patient populations dynamically, with properties that include patient specific therapeutic windows for drug activity and the eventual elimination of the current practice of developing drugs by the current axiom of maximum potency where adverse reactions are handled by dosing. We envision adaptive therapeutics to be an alternative to the current trajectory of personalized medicine, which depends on institutions having access to patients’ personal genome for clinical purposes. Instead, adaptive compounds are programmed to recognize and adapt to the personalized chemistry of diverse people in the patient population and thus maintain privacy.
Agriculture has a similarly significant application: adaptive synthetic humic substances that detect molecular soil chemistry and respond to the regional growing requirements by adapting their diverse properties. Properties include dynamic changes to ion transport, water and carbon sequestration without changing the material formulation for each region or customer. Adaptive synthetic humic compounds may obsolete current agrochemicals and perhaps eliminate the need for genetically engineered organisms by an active process that is functionally similar to adaptive therapeutics, where the adaptive humic compounds nurture agricultural products as they grow. The same adaptive organic compound breakthroughs are possible in areas of specialty chemicals, environmental science, organic advanced materials, and all industries chemistry related.
An example of an adaptive organic compound advanced material application is practical invisibility for Unmanned Autonomous Systems (UAS). Making a UAS invisible is not currently possible but making it ‘practically’ invisible is an area of current research. Adaptive compounds could be designed to respond to optical effects to change their configurations and enable practical invisibility advanced materials for UAS and other military applications.
Adaptive compounds are also used as probes and sensors to precisely understand the molecular basis of organic matter. An example is systems biology. Systems biology is the science of identifying the molecular signaling pathways that are the basis for life. The problem with systems biology is resolution. Systems biology starts with novel supercomputing architectures for analyzing clinical data, which the co-founder of SUPRACHEM has also created. This informational knowledge understanding must be refined to be useful and SUPRACHEM adaptive compounds do this. Based upon systems biology analysis intelligence, SUPRACHEM adaptive compounds are designed as probes and sensors. These adaptive compounds validate the inferences of systems biology by using molecular recognition to detect biomarkers for example. When the adaptive compound detects a biomarker it then makes a change to its configuration, which is detected by laboratory instruments. Adaptive compound designed as probes have applications outside of the life sciences. Probe adaptive compounds may be used to detect hazardous materials in the environment before the toxic substances are an environmental threat.
SUPRACHEM'S
Time To TRANSFORM CHEMISTRY
Adaptive Compounds Video
on YouTube
SUPRACHEM’S supramolecular engineering platform, QAI, is a revolutionary technology for organic molecule design, analysis and synthesis through the design and programming of molecular systems by engineering the particle information they exchange. This harnesses the natural processes of molecular self-organization, producing compounds with the functional capability of responding to external environmental solicitations by dynamic modification of their molecular constitution through particle component exchange and structural reorganization. The result is intelligent adaptive molecules with evolutive chemistry that demonstrate new molecular capabilities.
Applications of SUPRACHEM adaptive compounds and evolutive chemistry span all industries from the life sciences, agriculture, and advanced materials, to environmental applications and beyond. SUPRACHEM’S adaptive compounds are fundamentally novel, easily synthesized and manufactured, and have capabilities that extend beyond existing chemical products.
ADAPTIVE COMPOUNDS OVERVIEW
QAI Output: (Background) AGE Crosslink Breaker Adaptive Compound (Including Van Der Waal's Radius Overlays)
